For the third and final time this year, Roscosmos launched its Progress resupply vehicle to the International Space Station. The flight is the fourth cargo resupply Station mission from Russia this year, with Soyuz MS-14 flying in an uncrewed cargo configuration.
Liftoff occurred at 04:34:11 EST (09:34:11 UTC) from Site No. 31/6 at the Baikonur Cosmodrome in Kazakhstan. Progress then performed a three-day orbital rendezvous with the Station, arriving on Monday, 9 December for an automated docking.